PTPRCAP / CD45AP Antibody
364€ (100 µg)
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935106861
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name
PTPRCAP / CD45AP Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx236943
tested applications
ELISA, WB, IHC
Description
PTPRCAP / CD45AP Antibody is a Rabbit Polyclonal against PTPRCAP / CD45AP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PTPRCAP / CD45AP |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14761 |
| Gene ID | 5790 |
| OMIM | 601577 |
| Alias | LPAP,CD45-AP,PTPRCAP,CD45-associated protein,Lymphocyte phosphatase-associated phosphoprotein,PTPRC-associated protein,Protein tyrosine phosphatase receptor type C-associated protein |
| Background | Antibody anti-PTPRCAP |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Protein Tyrosine Phosphatase Receptor Type C Associated Protein (PTPRCAP), also known as CD45-associated protein, is a regulatory component of the CD45 phosphatase complex. CD45 is a transmembrane protein tyrosine phosphatase expressed on all nucleated hematopoietic cells and is essential for T-cell receptor (TCR) and B-cell receptor (BCR) signaling. PTPRCAP modulates CD45 activity, influencing immune cell activation, proliferation, and differentiation. It contributes to the regulation of lymphocyte signaling thresholds, thereby impacting immune responses and tolerance. Alterations in PTPRCAP expression or function are implicated in immune-related disorders, including autoimmunity and immunodeficiency. The protein plays a role in maintaining immune homeostasis and is a subject of interest for therapeutic interventions targeting immune dysregulation. Further studies are needed to clarify its precise mechanisms and broader biological roles in immune signaling.
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