PTPN11 (pY542) Antibody
208€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
PTPN11 (pY542) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000318
Tested Applications
ELISA, WB
Description
PTPN11 (pY542) Antibody is a Rabbit Polyclonal antibody against PTPN11 (pY542). The protein encoded by this gene is a member of the protein tyrosine phosphatase (pYP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as pTosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: PTPN11 (pY542) Immunogen: A synthetic phosphorylated peptide around Y542 of human PTPN11. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 68 kDa Observed MW: 72 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q06124 |
| Gene ID | 5781 |
| NCBI Accession | NP_002825.3 |
| Background | Antibody anti-PTPN11 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
PTPN11 (pY542) Antibody
PTPN11 (pY542) Antibody is a Rabbit Polyclonal antibody against PTPN11 (pY542). The protein encoded by this gene is a me…
Ver producto
Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) Antibody
PTPN11 Antibody is a Rabbit Polyclonal antibody against PTPN11. The protein encoded by this gene is a member of the prot…
Ver producto
Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11) Antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be sign…
Ver producto