Pterin-4 Alpha-Carbinolamine Dehydratase 1 (PCBD1) Antibody
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Description
PCBD1 Antibody is a Rabbit Polyclonal antibody against PCBD1. This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pterin-4 Alpha-Carbinolamine Dehydratase 1 (PCBD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61457 |
| Gene ID | 5092 |
| NCBI Accession | NP_000272.1 |
| Background | Antibody anti-PCBD1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Pterin-4 Alpha-Carbinolamine Dehydratase 1 (PCBD1) Antibody
PCBD1 Antibody is a Rabbit Polyclonal antibody against PCBD1. This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
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