PR/SET Domain 1 (PRDM1) Antibody

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Description
PRDM1/Blimp1 is a repressor of beta interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: PR/SET Domain 1 (PRDM1) Immunogen: Purified recombinant fragment of human PRDM1 expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 88 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75626 |
| Gene ID | 639 |
| Background | Antibody anti-PRDM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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PR/SET Domain 1 (PRDM1) Antibody
PRDM1/Blimp1 is a repressor of beta interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
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PR/SET Domain 1 (PRDM1) Antibody
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
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