Proto-Oncogene Mas (MAS1) Antibody (HRP)

Este producto es parte de MAS1 proto-oncogene
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169€ (20 µg)

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935106861
info@markelab.com
name
Proto-Oncogene Mas (MAS1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx304460
tested applications
ELISA

Description

MAS1 Antibody (HRP) is a Rabbit Polyclonal against MAS1 conjugated to HRP.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Proto-Oncogene Mas (MAS1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P04201
Gene ID
4142
OMIM
165180
Alias
MAS1,MAS,angiotensin 1-7 receptor ,MAS1 proto-oncogene G protein-coupled receptor,MAS1 proto-oncogene, MasR, Mgra
Background
Antibody anti-MAS1
Status
RUO

Descripción

MAS1 is a gene that encodes a G protein-coupled receptor (GPCR) involved in various physiological processes, including cardiovascular regulation, neuronal signaling, and cellular proliferation. It was originally identified as a proto-oncogene due to its potential role in tumorigenesis. MAS1 is involved in signaling pathways that regulate the growth and differentiation of cells. It is also known for its interaction with the angiotensin peptide, particularly in the regulation of blood pressure and fluid balance. MAS1 functions in mediating the effects of angiotensin peptides on vascular smooth muscle and endothelial cells, contributing to vasodilation and regulating blood pressure. Studies suggest that MAS1 may play a protective role in cardiovascular health by modulating angiotensin-induced vasoconstriction. Dysregulation of MAS1 signaling has been implicated in various cancers and cardiovascular diseases, and research into its role as a tumor suppressor or oncogene could provide novel insights for therapeutic strategies.

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