Protein Z Dependent Protease Inhibitor (SERPINA10) Antibody
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935106861
info@markelab.com
Precio
364€ (100 µg)
Antibody anti-SERPINA10
proveedor
Abbexareference
abx237740Tested Applications
ELISA, WB, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
SERPINA10 Antibody is a Mouse Monoclonal against SERPINA10.
Background
SERPINA10 is a gene encoding the protein Z-dependent protease inhibitor (ZPI), which is a member of the serpin (serine protease inhibitor) superfamily. The SERPINA10 gene is located on chromosome 14q32.1 and plays a critical role in the regulation of coagulation, specifically by inhibiting factors involved in the blood clotting cascade. ZPI is unique among the serpin family members because its inhibitory activity is modulated by the presence of protein Z, a cofactor that enhances its ability to inhibit coagulation factors. The understanding of SERPINA10 is essential in the context of hemostasis and thrombosis, as abnormalities in its function can lead to a predisposition to thrombotic disorders.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
Protein Z Dependent Protease Inhibitor (SERPINA10)
host
Mouse
isotype
IgG1
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC, IF/ICC
purity
≥ 95% (SDS-PAGE)
purification
Purified by Protein A and Protein G affinity chromatography.
recommended dilution
WB: 1/1500 - 1/6000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA10
dry ice
No
availability
Shipped within 5-12 working days.
alias
PZI,ZPI,Protein Z-dependent protease inhibitor,Serpin A10,PZ-dependent protease inhibitor
uniprot id
note
Concentration: 2 mg/ml - Validity: 12 months.
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