anti- SERPINA10 antibody

Este producto es parte de SERPINA10 - serpin family A member 10
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935106861
info@markelab.com
name
anti- SERPINA10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07740
tested applications
ELISA, WB, IHC, IF

Description

Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
Primary Antibodies
Immunogen Target
serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 10
Host
Mouse
Reactivity
human
Recommended Dilution
WB: 1:1500-1:6000; IF: 1:50-1:500; IHC: 1:50-1:500
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
4F10
Observed MW
51 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9UK55
Gene ID
51156
Alias
PZI,ZPI,Protein Z-dependent protease inhibitor,Serpin A10,PZ-dependent protease inhibitor
Background
Antibody anti-SERPINA10
Status
RUO
Note
This product is for research use only.

Descripción

SERPINA10 is a gene encoding the protein Z-dependent protease inhibitor (ZPI), which is a member of the serpin (serine protease inhibitor) superfamily. The SERPINA10 gene is located on chromosome 14q32.1 and plays a critical role in the regulation of coagulation, specifically by inhibiting factors involved in the blood clotting cascade. ZPI is unique among the serpin family members because its inhibitory activity is modulated by the presence of protein Z, a cofactor that enhances its ability to inhibit coagulation factors. The understanding of SERPINA10 is essential in the context of hemostasis and thrombosis, as abnormalities in its function can lead to a predisposition to thrombotic disorders.

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