Protein Z Dependent Protease Inhibitor (SERPINA10) Antibody

Name: Protein Z Dependent Protease Inhibitor (SERPINA10) Antibody
Brand: Abbexa
SKU: abx003563
Price: 195 EUR
Availability: OnlineOnly

Este producto es parte de SERPINA10 - serpin family A member 10

Pida mas información

935106861

info@markelab.com

Precio

195€ (20 µl)

Antibody anti-SERPINA10

proveedor

Abbexa

reference

abx003563

Tested Applications

ELISA, WB, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

SERPINA10 Antibody is a Rabbit Polyclonal antibody against SERPINA10. The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.

Background

SERPINA10 is a gene encoding the protein Z-dependent protease inhibitor (ZPI), which is a member of the serpin (serine protease inhibitor) superfamily. The SERPINA10 gene is located on chromosome 14q32.1 and plays a critical role in the regulation of coagulation, specifically by inhibiting factors involved in the blood clotting cascade. ZPI is unique among the serpin family members because its inhibitory activity is modulated by the presence of protein Z, a cofactor that enhances its ability to inhibit coagulation factors. The understanding of SERPINA10 is essential in the context of hemostasis and thrombosis, as abnormalities in its function can lead to a predisposition to thrombotic disorders.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Protein Z Dependent Protease Inhibitor (SERPINA10)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IF/ICC

purification

Purified by affinity chromatography.

recommended dilution

ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

100 µl

size 3

2 × 100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

SERPINA10

dry ice

availability

Shipped within 5-10 working days.

alias

PZI,ZPI,Protein Z-dependent protease inhibitor,Serpin A10,PZ-dependent protease inhibitor

uniprot id

https://www.uniprot.org/uniprotkb/Q9UK55

gene id

https://www.ncbi.nlm.nih.gov/gene/51156

NCBI accession

NP_001094077.1

note

Concentration: > 0.2 mg/ml -

Quizá le pueda interesar