Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody (FITC)
598€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx412688
tested applications
FCM
Description
Receptor-Type Tyrosine-Protein Phosphatase C (CD45) Antibody (FITC) is a Rat Monoclonal antibody against Receptor-Type Tyrosine-Protein Phosphatase C (CD45).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) |
| Host | Rat |
| Reactivity | Dog |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG2b |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | LCA,LY5,B220,CD45,L-CA,T200,CD45R,GP180,IMD105,CD45,Leukocyte common antigen,Receptor-type tyrosine-protein phosphatase C |
| Background | Antibody anti-PTPRC |
| Status | RUO |
| Note | Concentration: 0.1 mg/ml - |
Descripción
PTPRC, also known as CD45, is a receptor-type tyrosine phosphatase primarily expressed in hematopoietic cells. It regulates antigen receptor signaling in lymphocytes by dephosphorylating inhibitory residues on Src family kinases such as Lck and Fyn. Structurally, PTPRC has an extracellular domain, a single transmembrane region, and two cytoplasmic phosphatase domains, with the first being catalytically active. It is critical for T-cell and B-cell activation, development, and immune response regulation. Mutations in PTPRC are linked to severe immunodeficiency disorders, including SCID, and its overexpression is associated with autoimmune diseases and leukemia.
Related Products
APC Anti-Rat CD45 (OX-1)
Ver ProductoAPC Anti-Mouse CD45(30-F11)
Ver Producto