Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Antibody
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935106861
info@markelab.com
Precio
250€ (50 µl)
Antibody anti-PTPRB
proveedor
Abbexareference
abx320809Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
PTPRB Antibody is a Rabbit Polyclonal against PTPRB.
Background
PTPRB is a member of the receptor-type protein tyrosine phosphatases (RPTPs), which regulate tyrosine phosphorylation-dependent signaling. PTPRB plays an essential role in vascular development and endothelial cell function. It has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, of which one is enzymatically active. PTPRB is expressed predominantly in endothelial cells and modulates vascular permeability, angiogenesis, and blood vessel remodeling. It is involved in suppressing VEGF receptor signaling to maintain endothelial quiescence. Dysregulation of PTPRB has been implicated in diseases such as vascular malformations and cancers involving aberrant angiogenesis.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Protein Tyrosine Phosphatase Receptor Type B (PTPRB)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purification
Antigen Affinity Chromatography.
buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
PTPRB
dry ice
No
availability
Shipped within 5-10 working days.
alias
PTPB,HPTPB,VEPTP,HPTP-BETA,R-PTP-BETA,Vascular endothelial protein tyrosine phosphatase,Protein-tyrosine phosphatase beta,Receptor-type tyrosine-protein phosphatase beta
uniprot id
NCBI accession
NM_002837.5
note
This product is for research use only.
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