Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Protein

Name: Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) Protein
Brand: Abbexa
SKU: abx068770
Price: 225 EUR
Availability: OnlineOnly

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type

Pida mas información

935106861

info@markelab.com

Precio

225€ (10 µg)

Protein PTPRB

proveedor

Abbexa

reference

abx068770

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Protein Tyrosine Phosphatase Receptor Type B (PTPRB) is a recombinant Human protein produced in E. coli using Prokaryotic expression.

Background

PTPRB is a member of the receptor-type protein tyrosine phosphatases (RPTPs), which regulate tyrosine phosphorylation-dependent signaling. PTPRB plays an essential role in vascular development and endothelial cell function. It has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, of which one is enzymatically active. PTPRB is expressed predominantly in endothelial cells and modulates vascular permeability, angiogenesis, and blood vessel remodeling. It is involved in suppressing VEGF receptor signaling to maintain endothelial quiescence. Dysregulation of PTPRB has been implicated in diseases such as vascular malformations and cancers involving aberrant angiogenesis.

Características del producto

origin

Human

host

E. coli

immunogen target

Protein Tyrosine Phosphatase Receptor Type B (PTPRB)

host

E. coli

conjugation

Unconjugated

form

Lyophilized

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

PTPRB

dry ice

availability

Shipped within 5-7 working days.

alias

PTPB,HPTPB,VEPTP,HPTP-BETA,R-PTP-BETA,Vascular endothelial protein tyrosine phosphatase,Protein-tyrosine phosphatase beta,Receptor-type tyrosine-protein phosphatase beta

uniprot id

https://www.uniprot.org/uniprotkb/P23467

note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.

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