Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody
208€ (20 µl)
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Name
Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001496
Tested Applications
WB, IF/ICC
Description
PTPN2 Antibody is a Rabbit Polyclonal antibody against PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Immunogen: Recombinant protein corresponding to PTPN2. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 48 kDa Observed MW: 45 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P17706 |
| Gene ID | 5771 |
| NCBI Accession | NP_536348.1 |
| Background | Antibody anti-PTPN2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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