Protein S100-A1 (S100A1) Antibody

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Description
S100A1 (S100 alpha/S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Protein S100-A1 (S100A1) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Purification | Unpurified ascites. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | Ascitic fluid containing 0.03% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P23297 |
Gene ID | 6271 |
OMIM | 176940 |
Background | Antibody anti-S100A1 |
Status | RUO |
Note | Concentration: Not determined. - |
Descripción
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S100A1 (S100 alpha/S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
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