Protein Patched Homolog 1 (PTCH1) Antibody
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Description
Protein Patched Homolog 1 (PTCH1) Antibody is a Rabbit Polyclonal antibody for the detection of PTCH1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein Patched Homolog 1 (PTCH1) Immunogen: patched homolog 1 |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 161 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13635 |
| Gene ID | 5727 |
| OMIM | 109400 |
| Background | Antibody anti-PTCH1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
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Protein Patched Homolog 1 (PTCH1) Antibody
Protein Patched Homolog 1 (PTCH1) Antibody is a Rabbit Polyclonal antibody for the detection of PTCH1.
Ver Producto