Protein CutA (CUTA) Antibody (Biotin)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Protein CutA (CUTA) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx316847
tested applications
ELISA
Description
CUTA Antibody (Biotin) is a Rabbit Polyclonal against CUTA conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein CutA (CUTA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60888 |
| Gene ID | 51596 |
| NCBI Accession | NP_001014433.1, NM_001014433.2, NP_001014837.1, NM_001014837.1, NP_001014838.1, NM_001014838.1, NP_001014840.1, NM_001014840.1 |
| OMIM | 616953 |
| Alias | ACHAP,C6orf82 |
| Background | Antibody anti-CUTA |
| Status | RUO |
Descripción
The cutA divalent cation tolerance homolog (CUTA) is a highly conserved protein that plays a role in cellular tolerance to divalent metal cations, such as copper, zinc, and nickel. It is ubiquitously expressed in various tissues and is localized in both the cytoplasm and mitochondria, where it is thought to regulate metal ion homeostasis and protect cells from metal-induced toxicity. CUTA is implicated in modulating mitochondrial function and redox balance by ensuring appropriate cation levels, which are essential for enzymatic activities and structural stability within the organelle. Dysregulation of CUTA expression or function has been associated with mitochondrial dysfunction and oxidative stress, which are linked to neurodegenerative diseases, including Alzheimer's disease. CUTA has also been suggested to have a role in copper homeostasis, as it may influence copper-binding proteins and prevent copper-induced oxidative damage. Although its precise mechanisms of action remain under investigation, CUTA's involvement in metal ion detoxification and mitochondrial health makes it a potential target for understanding and treating conditions associated with metal ion imbalance.
Related Products
Human ACHAP (Acetylcholinesterase Associated Protein) ELISA Kit
Ver Producto
Protein CutA (CUTA) Antibody
May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).
Ver Producto