Protein CBFA2T1 (RUNX1T1) Antibody

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Description
Runt-Related Transcription Factor 1; Translocated To, 1 (Cyclin D-Related) Antibody is a Rabbit Polyclonal antibody against Runt-Related Transcription Factor 1; Translocated To, 1 (Cyclin D-Related).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein CBFA2T1 (RUNX1T1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q06455 |
| Gene ID | 862 |
| NCBI Accession | NP_001185554.1, NM_001198625.1, NP_001185555.1, NM_001198626.1 |
| OMIM | 133435 |
| Background | Antibody anti-RUNX1T1 |
| Status | RUO |
Descripción
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Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588).
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Protein CBFA2T1 (RUNX1T1) Antibody
Runt-Related Transcription Factor 1; Translocated To, 1 (Cyclin D-Related) Antibody is a Rabbit Polyclonal antibody against Runt-Related Transcription Factor 1; Translocated To, 1 (Cyclin D-Related).
Ver Producto