Protein C Receptor, Endothelial (PROCR) Antibody (FITC)
169€ (20 µg)
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935106861
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name
Protein C Receptor, Endothelial (PROCR) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx106799
Description
Endothelial protein C receptor Antibody (FITC) is a Rabbit Polyclonal antibody against Endothelial protein C receptor conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein C Receptor, Endothelial (PROCR) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UNN8 |
| Gene ID | 10544 |
| OMIM | 600646 |
| Alias | CCCA,EPCR,CCD41,Endothelial protein C receptor, Activated protein C receptor,APC receptor,Endothelial cell protein C receptor |
| Background | Antibody anti-PROCR |
| Status | RUO |
Descripción
PROCR, also known as the endothelial protein C receptor (EPCR), is a critical component of the protein C anticoagulant pathway. This pathway has essential roles in regulating blood coagulation, inflammation, and maintaining vascular integrity. PROCR is primarily expressed on endothelial cells lining blood vessels and binds to activated protein C (APC) to enhance its anticoagulant effects. This interaction is vital for limiting thrombosis, mitigating inflammation, and preserving the barrier function of blood vessels, especially in response to inflammatory and coagulatory challenges. Recent research has revealed additional roles for PROCR, including functions in immune response modulation, cell proliferation, and tissue regeneration.
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