Proteinase-Activated Receptor 4 (F2RL3) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Proteinase-Activated Receptor 4 (F2RL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx016047
tested applications
ELISA, WB, IHC
Description
Prostate apoptosis response 4 (F2RL3) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis.It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults.F2RL3 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.The tumor suppressor WT1 represses and activates transcription.The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor.F2RL3 is a WT1 interacting protein that also functions as a transcriptional repressor.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Proteinase-Activated Receptor 4 (F2RL3) Immunogen: Purified recombinant fragment of PAR4 (aa1-330) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96IZ0 |
| Gene ID | 5074 |
| OMIM | 601936 |
| Background | Antibody anti-F2RL3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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