Prostate-Specific Antigen / PSA (KLK3) Antibody

Prostate-Specific Antigen / PSA (KLK3) Antibody
195€ (20 µl)

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Name
Prostate-Specific Antigen / PSA (KLK3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001669
Tested Applications
ELISA, WB, IHC, IF/ICC, IP

Description

KLK3 Antibody is a Rabbit Polyclonal antibody against KLK3. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Prostate-Specific Antigen / PSA (KLK3)
Immunogen: Recombinant protein corresponding to KLK1B3. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 29 kDa  Observed MW: 34 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC, IP
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07288
Gene ID
354
NCBI Accession
NP_001639.1
OMIM
176820
Background
Antibody anti-KLK3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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