Prostaglandin E Synthase 2 (PTGES2) Antibody

Este producto es parte de PTGES - Prostaglandin E synthase
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416€ (200 µl)

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935106861
info@markelab.com
name
Prostaglandin E Synthase 2 (PTGES2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433200
tested applications
P-ELISA, WB, IHC

Description

PTGES2 Antibody is a Goat Polyclonal antibody against PTGES2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Prostaglandin E Synthase 2 (PTGES2)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IHC
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
80142
NCBI Accession
NP_079348.1, NP_945176.1
Alias
C9orf15,GBF-1,GBF1,PGES2,mPGES-2,Membrane-associated prostaglandin E synthase-2
Background
Antibody anti-PTGES2
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

Prostaglandin E Synthase 2 (PTGES2) is an enzyme involved in prostaglandin biosynthesis specifically converting prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2) which is a critical lipid mediator in inflammation fever and pain responses PTGES2 is localized in the cytoplasm and functionally distinct from its microsomal counterpart (mPGES-1) It is constitutively expressed in various tissues and its activity is regulated by cellular stimuli such as cytokines or stress signals PTGES2-derived PGE2 plays a role in modulating immune responses and tissue homeostasis Dysregulation of PTGES2 expression has been implicated in chronic inflammatory diseases such as arthritis and inflammatory bowel disease as well as cancer progression due to PGE2’s role in tumorigenesis and immune evasion PTGES2 is also linked to reproductive functions and fever response through its regulation of the hypothalamic-pituitary-adrenal axis

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