Properdin (CFP) Antibody

Properdin (CFP) Antibody
312€ (60 µl)

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Name
Properdin (CFP) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx004133
Tested Applications
WB, IHC, IF/ICC

Description

CFP Antibody is a Rabbit Polyclonal antibody against CFP. This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Properdin (CFP)
Immunogen: Recombinant fusion protein corresponding to human CFP
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 51 kDa  Observed MW: 50 kDa
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P27918
Gene ID
5199
NCBI Accession
NP_001138724.1
Background
Antibody anti-CFP
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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