Programmed Cell Death Protein 4 (PDCD4) Antibody
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Description
Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) Antibody is a Rabbit Polyclonal antibody against Programmed Cell Death 4 (Neoplastic Transformation Inhibitor).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Programmed Cell Death Protein 4 (PDCD4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q53EL6 |
| Gene ID | 27250 |
| NCBI Accession | NP_055271.2, NM_014456.4, NP_663314.1, NM_145341.3 |
| OMIM | 608610 |
| Background | Antibody anti-PDCD4 |
| Status | RUO |
Descripción
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PDCD4 antibody
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
Ver ProductoPDCD4 antibody
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
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