anti- PDCD4 antibody

anti- PDCD4 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-PDCD4

proveedor

FineTest

reference

FNab06240

Tested Applications

ELISA, WB, IHC

reactivity

human

status

RUO

clonality

monoclonal

Descripción

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).

Características del producto

category

Primary Antibodies


clonality

monoclonal


reactivity

human


immunogen target

programmed cell death 4(neoplastic transformation inhibitor)


host

Mouse


isotype

IgG1


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

56 kDa


purity

≥95% as determined by SDS-PAGE


purification

Protein A+G purification


recommended dilution

WB: 1:1000-1:4000; IHC: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

PDCD4


alias

H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a


note

This product is for research use only.


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