anti- PDCD4 antibody
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Precio
Precio a consultar
Antibody anti-PDCD4
proveedor
FineTestreference
FNab06240Tested Applications
ELISA, WB, IHCreactivity
humanstatus
RUOclonality
monoclonalDescripción
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
Características del producto
category
Primary Antibodies
clonality
monoclonal
reactivity
human
immunogen target
programmed cell death 4(neoplastic transformation inhibitor)
host
Mouse
isotype
IgG1
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC
observerd MW
56 kDa
purity
≥95% as determined by SDS-PAGE
purification
Protein A+G purification
recommended dilution
WB: 1:1000-1:4000; IHC: 1:20-1:200
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
PDCD4
alias
H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a
uniprot id
note
This product is for research use only.
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