Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Antibody

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357.5€ (100 µg)

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935106861
info@markelab.com
name
Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036829
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the PLOD2 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2)
Immunogen: Recombinant fragment corresponding to 120-325 AA of human PLOD2.
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml.
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 85 kDa, 87 kDa
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Background
Antibody anti-PLOD2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Antibody

PLOD2 Antibody is a Rabbit Polyclonal antibody against PLOD2. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

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