PLOD2-Specific antibody

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935106861
info@markelab.com
name
PLOD2-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06552
tested applications
ELISA, WB, IHC, IF, IP

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:100-1:400; IF: 1:10-1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
85 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O00469
Alias
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2,Lysyl hydroxylase 2 (LH2),PLOD2
Background
Antibody anti-PLOD2
Status
RUO
Note
Mol. Weight 85 kDa

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Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Antibody

PLOD2 Antibody is a Rabbit Polyclonal antibody against PLOD2. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

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