Probable Histidine-tRNA Ligase, Mitochondrial (HARS2) Antibody (FITC)
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Description
Probable histidine--tRNA ligase, mitochondrial Antibody (FITC) is a Rabbit Polyclonal antibody against Probable histidine--tRNA ligase, mitochondrial conjugated to FITC.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Probable Histidine-tRNA Ligase, Mitochondrial (HARS2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49590 |
| Gene ID | 23438 |
| NCBI Accession | NP_001265660.1, NM_001278731.1 |
| OMIM | 600783 |
| Background | Antibody anti-HARS2 |
| Status | RUO |
Descripción
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
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