G-Protein Coupled Receptor 151 (GPR151) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
G-Protein Coupled Receptor 151 (GPR151) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx031311
tested applications
ELISA, WB
Description
Orphan receptor.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G-Protein Coupled Receptor 151 (GPR151) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TDV0 |
| Gene ID | 134391 |
| OMIM | 618487 |
| Alias | GPR151,GALR4,G-protein coupled receptor PGR7,galanin receptor 4,GALRL, GPCR, GPCR-2037, PGR7 |
| Background | Antibody anti-GPR151 |
| Status | RUO |
Descripción
GPR151 is an orphan G protein-coupled receptor (GPCR) predominantly expressed in the central nervous system, particularly in regions such as the habenula, a brain area involved in regulating mood, reward, and aversion responses. GPR151 is thought to play a role in modulating neuronal signaling pathways associated with addiction, anxiety, and depression. Its expression is tightly regulated by neuronal activity, suggesting it may function in fine-tuning synaptic signaling and maintaining neural circuit stability. Emerging evidence indicates that GPR151 is involved in behaviors linked to motivation, pain regulation, and responses to negative stimuli, particularly through its role in habenular circuits. Dysregulation of GPR151 expression has been associated with psychiatric disorders, including depression and substance abuse, where impaired habenular function disrupts mood and reward processing. Although its endogenous ligand remains unknown, GPR151 is considered a promising target for understanding mood disorders, addiction, and motivational behavior, highlighting its potential for therapeutic interventions in neuropsychiatric diseases.
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