Premature Ovarian Failure, 1B (POF1B) Antibody
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Description
Premature Ovarian Failure, 1B Antibody is a Rabbit Polyclonal antibody against Premature Ovarian Failure, 1B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Premature Ovarian Failure, 1B (POF1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WVV4 |
| Gene ID | 79983 |
| NCBI Accession | NP_001294869.1, NM_001307940.1 |
| OMIM | 300603 |
| Background | Antibody anti-POF1B |
| Status | RUO |
Descripción
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POF1B antibody
Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
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Premature Ovarian Failure, 1B (POF1B) Antibody
Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
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Premature Ovarian Failure, 1B (POF1B) Antibody
Premature Ovarian Failure, 1B Antibody is a Rabbit Polyclonal antibody against Premature Ovarian Failure, 1B.
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