POU Domain, Class 5, Transcription Factor 1 (POU5F1) Antibody

273€ (100 µl)
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935106861
info@markelab.com
name
POU Domain, Class 5, Transcription Factor 1 (POU5F1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx132489
tested applications
WB, IHC, IF/ICC
Description
POU Domain, Class 5, Transcription Factor 1 (POU5F1) Antibody is a Mouse Monoclonal antibody for the detection of POU Domain, Class 5, Transcription Factor 1 (POU5F1).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | POU Domain, Class 5, Transcription Factor 1 (POU5F1) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2a Kappa |
Clone ID | M370 |
Purification | Protein A and Protein G affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Background | Antibody anti-POU5F1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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