POU5F1 antibody
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935106861
info@markelab.com
name
POU5F1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05964
tested applications
ELISA, WB, IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | POU class 5 homeobox 1 (POU5F1) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:4000-1:20000; IHC: 1:200-1:1000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 0H7 |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q01860 |
| Gene ID | 5460 |
| Alias | POU domain, class 5, transcription factor 1,Octamer-binding protein 3 (Oct-3),Octamer-binding protein 4 (Oct-4),Octamer-binding transcription factor 3 (OTF-3),POU5F1,OCT3,OCT4,OTF3 |
| Background | Antibody anti-POU5F1 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
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POU5F1 antibody
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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