POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
383.5€ (100 µl)
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Name
POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx016043
Tested Applications
ELISA
Description
Oct4: octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, also known as POU5F1 (POU class 5 homeobox 1), octamerbinding transcription factor-3 (Oct-3, Otf-3), modulates embryonic stem (ES) cell populations by influencing lineage commitment.Entrez Protein NP_002692.Oct-3/4 sustains stem-cell selfrenewal and differentiation pathways.Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development.Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene.In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells.Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: POU Class 5 Homeobox 1 / OCT4 (POU5F1) Immunogen: Purified recombinant fragment of Oct4 (aa193-360) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 38.5 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q01860 |
| Gene ID | 5460 |
| OMIM | 164177 |
| Background | Antibody anti-POU5F1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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