Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody

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Description
KCNQ1 Antibody is a Rabbit Polyclonal antibody against KCNQ1. KCNQ1 is a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P51787 |
Gene ID | 3784 |
NCBI Accession | NP_861463.1 |
Background | Antibody anti-KCNQ1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody
KCNQ1 Antibody is a Rabbit Polyclonal antibody against KCNQ1. KCNQ1 is a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.
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Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential.This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation.This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others.This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS.Alternatively spliced transcript variants have been found for this gene.
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Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) Antibody
This gene encodes a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a number of contiguous genes, which are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. This gene is also imprinted, with preferential expression from the maternal allele in some tissues, excluding cardiac muscle. Alternatively spliced transcripts encoding distinct isoforms have been described.
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