Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002160
tested applications
WB, IHC

Description

KCNH2 Antibody is a Rabbit Polyclonal antibody against KCNH2. This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB, IHC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q12809
Gene ID
3757
NCBI Accession
NP_000229.1
Background
Antibody anti-KCNH2
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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