Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody

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Description
KCNH2 Antibody is a Rabbit Polyclonal antibody against KCNH2. This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q12809 |
Gene ID | 3757 |
NCBI Accession | NP_000229.1 |
Background | Antibody anti-KCNH2 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody
KCNH2 Antibody is a Rabbit Polyclonal antibody against KCNH2. This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
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KCNH2 is a voltage-activated potassium channel belonging to the eag family.
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KCNH2 Antibody is a Rabbit Polyclonal against KCNH2.
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