Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Antibody
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Description
KCNN4 Antibody is a Rabbit Polyclonal against KCNN4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15554 |
| Gene ID | 3783 |
| OMIM | 602754 |
| Background | Antibody anti-KCNN4 |
| Status | RUO |
Descripción
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KCNN4 antibody
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
Ver ProductoKCNN4 antibody
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
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Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Antibody
KCNN4 Antibody is a Rabbit Polyclonal antibody against KCNN4. The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
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