KCNN4 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (KCNN4) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 8A11 |
| Observed MW | 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O15554 |
| Gene ID | 3783 |
| Alias | Intermediate conductance calcium-activated potassium channel protein 4 (SK4, SKCa 4, SKCa4),IKCa1 (IK1),KCa3.1,KCa4,Putative Gardos channel,KCNN4,IK1,IKCA1,KCA4,SK4 |
| Background | Antibody anti-KCNN4 |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Descripción
Related Products
KCNN4 antibody
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
Ver ProductoKCNN4 antibody
Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
Ver Producto
Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4) Antibody
KCNN4 Antibody is a Rabbit Polyclonal antibody against KCNN4. The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
Ver Producto