Porcine PLAUR/uPAR (Plasminogen Activator, Urokinase Receptor) ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | Porcine |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 4.688-300pg/ml |
Sensitivity | 2.813pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | A0A8D1E2A2 |
Alias | CD87,UPAR,URKR,U-PAR,Urokinase plasminogen activator surface receptor,Monocyte activation antigen Mo3 |
Background | Elisa kits for PLAUR |
Status | RUO |
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Porcine PLAUR/uPAR (Plasminogen Activator, Urokinase Receptor) ELISA Kit
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PLAUR antibody
Urokinase plasminogen activator surface receptor(uPAR, also known as PLAUR or CD87) is a 45-65 kDa, highly glycosylated, GPI-anchored membrane protein. It contains three homologous domains(D1-D3) of which the N-terminal one(D1) represents the uPA-binding domain. After binding to uPAR, urokinase plasminogen activator(uPA) cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodelling and in many human cancers, in which it frequently indicates poor prognosis.(PMID 20027185; 12461559)
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