Polymeric Immunoglobulin Receptor (PIGR) Antibody

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Description
PIGR Antibody is a Rabbit Polyclonal antibody against PIGR. This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Polymeric Immunoglobulin Receptor (PIGR) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P01833 |
Gene ID | 5284 |
NCBI Accession | NP_002635.2 |
Background | Antibody anti-PIGR |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Polymeric Immunoglobulin Receptor (PIGR) Antibody
PIGR Antibody is a Rabbit Polyclonal antibody against PIGR. This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Ver Producto
Polymeric Immunoglobulin Receptor (PIGR) Antibody
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
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