Polyadenylate-Binding Protein-Interacting Protein 2 (PAIP2) Antibody
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Description
Poly(A) Binding Protein Interacting Protein 2 (PAIP2) Antibody is a Rabbit Polyclonal antibody against Poly(A) Binding Protein Interacting Protein 2 (PAIP2).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Polyadenylate-Binding Protein-Interacting Protein 2 (PAIP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Validated in IHC-P and IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BPZ3 |
| Background | Antibody anti-PAIP2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
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Polyadenylate-Binding Protein-Interacting Protein 2 (PAIP2) Antibody
PAIP2 acts as a repressor in the regulation of translation initiation of poly (A) containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly (A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly (A) RNP structure organization.
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