PAIP2 antibody
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Description
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | poly(A) binding protein interacting protein 2 (PAIP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 26 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BPZ3 |
| Gene ID | 51247 |
| Alias | Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2, PAIP-2, Poly(A)-binding protein-interacting protein 2),PAIP2,PAIP2A |
| Background | Antibody anti-PAIP2 |
| Status | RUO |
| Note | Mol. Weight 26 kDa |
Descripción
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