Polyadenylate-Binding Protein-Interacting Protein 1 (PAIP1) Antibody
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Description
PAIP1 Antibody is a Rabbit Polyclonal against PAIP1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Polyadenylate-Binding Protein-Interacting Protein 1 (PAIP1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H074 |
| Gene ID | 10605 |
| NCBI Accession | NP_006442.2, NM_006451.4 |
| OMIM | 605184 |
| Background | Antibody anti-PAIP1 |
| Status | RUO |
Descripción
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Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.
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Polyadenylate-Binding Protein-Interacting Protein 1 (PAIP1) Antibody
PAIP1 Antibody is a Rabbit Monoclonal antibody against PAIP1. The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
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