PAIP1 antibody
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Description
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | poly(A) binding protein interacting protein 1 (PAIP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat, Monkey |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa,51 kDa,40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H074 |
| Gene ID | 10605 |
| Alias | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1),PAIP1 |
| Background | Antibody anti-PAIP1 |
| Status | RUO |
| Note | Mol. Weight 60 kDa, 51 kDa, 40 kDa |
Descripción
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