Poly(A)-Specific Ribonuclease PARN (PARN) Antibody
169€ (20 µg)
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name
Poly(A)-Specific Ribonuclease PARN (PARN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110104
tested applications
ELISA, WB, IHC, IF/ICC
Description
Poly(A)-specific ribonuclease PARN Antibody is a Rabbit Polyclonal antibody against Poly(A)-specific ribonuclease PARN.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Poly(A)-Specific Ribonuclease PARN (PARN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95453 |
| Gene ID | 5073 |
| NCBI Accession | NP_001127949.1, NM_001134477.2 |
| OMIM | 604212 |
| Background | Antibody anti-PARN |
| Status | RUO |
Descripción
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Human PARN (Poly (A) -specific ribonuclease PARN) ELISA Kit
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PARN antibody
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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