Poly(A) Polymerase I (PCNB) Antibody
260€ (50 µg)
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name
Poly(A) Polymerase I (PCNB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377523
tested applications
ELISA, WB
Description
Poly(A) Polymerase I (PCNB) Antibody is a Rabbit polyclonal antibody for the detection of E. coli (strain K12) Poly(A) Polymerase I (PCNB).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Poly(A) Polymerase I (PCNB) |
| Host | Rabbit |
| Reactivity | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0ABF1 |
| NCBI Accession | NP_414685.4 |
| Background | Antibody anti-PARN |
| Status | RUO |
Descripción
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The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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