Poly A Specific Ribonuclease (PARN) Antibody
637€ (100 µl)
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935106861
info@markelab.com
name
Poly A Specific Ribonuclease (PARN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx114576
tested applications
ELISA, WB, IHC
Description
Poly(A)-Specific Ribonuclease (Deadenylation Nuclease) Antibody is a Rabbit Polyclonal antibody against Poly(A)-Specific Ribonuclease (Deadenylation Nuclease).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Poly A Specific Ribonuclease (PARN) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95453 |
| Gene ID | 5073 |
| NCBI Accession | NP_001127949.1, NM_001134477.2, NP_001229921.1, NM_001242992.1, NP_002573.1, NM_002582.3 |
| OMIM | 604212 |
| Background | Antibody anti-PARN |
| Status | RUO |
Descripción
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Human PARN (Poly (A) -specific ribonuclease PARN) ELISA Kit
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PARN antibody
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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