Poliovirus Receptor Related Protein 3 (NECTIN3) Antibody
292.5€ (80 µl)
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935106861
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name
Poliovirus Receptor Related Protein 3 (NECTIN3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027068
tested applications
ELISA, WB
Description
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090) catenin (see MIM 116805) system in epithelial cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Poliovirus Receptor Related Protein 3 (NECTIN3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NQS3 |
| Alias | PPR3,PRR3,CD113,PVRL3,PVRR3,CDW113,NECTIN-3,Nectin cell adhesion molecule 3,Poliovirus receptor-related protein 3 |
| Background | Antibody anti-NECTIN3 |
| Status | RUO |
Descripción
Nectin cell adhesion molecule 3 (NECTIN3) is predominantly expressed in neural and testicular tissues, where it is essential for processes such as synapse formation and spermatogenesis. It forms trans-heterophilic interactions with other nectin family members, enabling precise cell-cell communication critical for the development and maintenance of specialized tissues. NECTIN3 is also involved in neuronal plasticity, where its expression affects synaptic strength and connectivity in the central nervous system.
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Poliovirus Receptor Related Protein 3 (NECTIN3) Antibody
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090) catenin (see MIM 116805) system in epithelial cells.
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