Platelet Glycoprotein 4 (CD36) Antibody (Biotin)

Este producto es parte de CD36 - CD36 molecule
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364€ (0.1 mg)

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935106861
info@markelab.com
name
Platelet Glycoprotein 4 (CD36) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx140904
tested applications
FCM

Description

Platelet Glycoprotein 4 (CD36) Antibody (Biotin) is a Mouse  against Platelet Glycoprotein 4 (CD36).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Platelet Glycoprotein 4 (CD36)
Host
Mouse
Reactivity
Human
Recommended Dilution
FCM: 1 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Biotin
Isotype
IgG1
Clone ID
P052
Size 1
0.1 mg
Tested Applications
FCM
Buffer
PBS solution with 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8°C. Do not freeze.
Dry Ice
No
UniProt ID
P16671
Gene ID
948
Alias
FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4
Background
Antibody anti-CD36
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.

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