Platelet Glycoprotein 4 (CD36) Antibody
312€ (60 µl)
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name
Platelet Glycoprotein 4 (CD36) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001251
tested applications
WB
Description
CD36 Antibody is a Rabbit Polyclonal antibody against CD36. CD36, also named as GP3B and GP4, seems to have numerous potential physiological functions. CD36 binds to collagen, thrombospondin, anionic phospholipids, long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.and oxidized LDL. CD36 may function as a cell adhesion molecule. It mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutation of CD36 will cause platelet glycoprotein IV deficiency which known as CD36 deficiency. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7). This antibody 18836-1-AP is raised against a synthesized peptide of 100-116 amino acids of CD36.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Platelet Glycoprotein 4 (CD36) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P16671 |
| Gene ID | 948 |
| NCBI Accession | NP_001120916.1 |
| Alias | FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4 |
| Background | Antibody anti-CD36 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.
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