Platelet Glycoprotein 4 (CD36) Antibody
299€ (0.1 mg)
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Name
Platelet Glycoprotein 4 (CD36) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139254
Tested Applications
FCM
Description
CD36 Antibody is a Mouse Monoclonal against CD36.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Platelet Glycoprotein 4 (CD36) Immunogen: Living Human myeloid cells. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgM Kappa |
| Clone ID | G280 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by precipitation and chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | TBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P16671 |
| Gene ID | 948 |
| Alias | FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4 |
| Background | Antibody anti-CD36 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.
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