Platelet Glycoprotein 4 (CD36) Antibody

Este producto es parte de CD36 - CD36 molecule
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221€ (50 µg)

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935106861
info@markelab.com
name
Platelet Glycoprotein 4 (CD36) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx327204
tested applications
ELISA, WB

Description

CD36 Antibody is a Rabbit Polyclonal against CD36.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Platelet Glycoprotein 4 (CD36)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P16671
Gene ID
948
Alias
FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4
Background
Antibody anti-CD36
Status
RUO

Descripción

CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.

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