Plasma Protease C1 Inhibitor (SERPING1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
SERPING1 Antibody is a Rabbit Polyclonal against SERPING1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Plasma Protease C1 Inhibitor (SERPING1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05155 |
| Gene ID | 710 |
| Alias | C1IN,C1NH,HAE1,HAE2,C1INH,Plasma protease C1 inhibitor,C1 esterase inhibitor,C1-inhibiting factor |
| Background | Antibody anti-SERPING1 |
| Status | RUO |
Descripción
SERPING1, also known as C1 esterase inhibitor (C1-INH), is a serine protease inhibitor that plays a critical role in regulating the complement system, a part of the immune response. SERPING1 is primarily responsible for controlling the activation of the C1 complex in the classical pathway of complement activation. Beyond complement regulation, it also inhibits several other proteases involved in the coagulation, fibrinolytic, and kinin-generating systems. SERPING1 mutations or deficiencies are strongly linked to hereditary angioedema (HAE), a potentially life-threatening condition characterized by uncontrolled swelling. SERPING1 is an important therapeutic target in diseases where inappropriate immune activation or excessive protease activity leads to tissue damage or inflammation. It is mainly synthesized in the liver and secreted into the bloodstream, where it circulates and exerts its regulatory effects.
Related Products
Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit
Human Plasma Protease C1 Inhibitor (SERPING1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human C1INH concentrations in serum, plasma and other biological fluids.
Ver Producto
Human Plasma Protease C1 Inhibitor / C1INH (SERPING1) ELISA Kit
Human Plasma Protease C1 Inhibitor / C1INH (SERPING1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Plasma Protease C1 Inhibitor / C1INH (SERPING1) concentrations in serum, , plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Complement 1 Inhibitor (Complement 1 Inhibitor)
Ver Producto
Plasma Protease C1 Inhibitor (SERPING1) Antibody (FITC)
SERPING1 Antibody (FITC) is a Rabbit Polyclonal against SERPING1 conjugated to FITC.
Ver Producto